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Wednesday, March 5, 2008

ROLE OF NONI IN OBESITY

From World Noni Research Foundation

ROLE OF NONI IN OBESE PATIENT

  • The levels of the fat-soluble antioxidants, vitamin E and carotenoids were significantly lower in patients with severe obesity as compared to normal weight subjects, whereas no differences in the concentrations of the B vitamins, folic acid and B12. Epidemiologic studies have demonstrated an association between increased intake of antioxidant vitamins such as vitamin E, carotenoids and vitamin C and reduced morbidity and mortality from coronary artery disease. This association has been explained on the basis of the LDL oxidative modification process, which involves the initiation of atherogenesis and its protection by oxidation of the LDL lipids. Extensive studies have shown an inverse association between CAD (coronary artery diseases) events and vitamin E and carotenoids intake. It has been demonstrated the ability of b-carotene to protect LDL against oxidation both in healthy subjects and in diabetic patients, with an emphasis on b-carotene derived from natural sources.
  • Noni is rich in all vitamins -Vit A, Vita C, Vita B complex, and with beta carotenoids. Noni contains all the trace minerals and all essential amino acids. Besides that it contains more than 150 PHYTONUTRIENTS. All this unique combination is only found in NONI. So it acts like a powerful antioxidants. So any obese paitent if taking Noni then it helps to prevent the formation of atherosclerotic plaques as it protects LDL lipids against oxidation. Noni juice is purely natural, the extract of Noni fruits. Flavonoids are a vast group of polyphenolic substances; with high antioxidant properties. Noni is rich with Flavonoids.
  • A significant reduction in plasma antioxidants in obese patients suggests a so far unrecognized CAD (coronary artery diseases) risk factor in these patients. Only a limited number of studies have dealt with antioxidants and obesity. Hence supplementation of Noni to the obese patient will prevent them from the attack of coronary artery diseases (CAD).
  • Lower serum levels of vitamin E were demonstrated in subjects with abdominal obesity. Vitamin E and b-carotene were significantly lower in plasma of obese boys and LDL of obese girls. Supplementation with Noni to obese children will fulfill the demand of vita E, and B-carotene in their body.
  • Another mechanism that potentially relates obesity to low antioxidants and enhanced oxidation involves hyperinsulinemia. Physiologically, severe obesity is characterized by hyperinsulinemia. Hence Noni supplementation helps to maintain the antioxidant level in the blood and thus prevents from arising of condition of hyperinsulinemia.
  • Low plasma antioxidants have been linked to oxidative modification of LDL, a process necessary for the generation of atherosclerotic plaque. Noni prevent the oxidative modification of LDL cholesterol by its high antioxidant properties.
  • There is an inverse relationship between plasma antioxidant vitamin carotenoids and vitamin E and cardiovascular diseases. Hence Noni prevents the possibility of many cardiac diseases in case of obese patients by its high power antioxidant properties. Indeed, some studies have shown enhanced oxidative stress and low concentrations of plasma antioxidants in patients with obesity.
  • As apparent from the preceding sections of this review, obesity is a major risk factor for the development of type 2 diabetes. Therefore, supplements that induce weight loss are useful for the prevention and/or treatment of diabetes. One such supplement is chromium which is available as chromium picolinate. The exact mechanism of action of chromium is not completely understood, but it has been shown that this trace element inhibits insulin secretion in isolated pancreatic islets. It should be recalled that hyperinsulinemia is a characteristic feature of obesity and it has been hypothesized that high plasma insulin levels may be responsible for excessive body weight gain. It has also been proposed that chromium may act as an insulin sensitizer in type 2 diabetes. It is interesting to note that the chromium concentration in the body appears to decline with age. Along with the age-associated deficiency in antioxidant defense systems, the age-dependent reduction in chromium levels may play a role in the high incidence of type 2 diabetes in elderly individuals. Noni contains this trace mineral chromium and those takes Noni daily helps them a lot from not only their obesity but also from the future diabetes situation.
  • CLA (Conjugated Linoleic Acid) may significantly help reduce body fat, and there's even recent evidence to support that it increases muscle tissue. In a general sense, what it's doing is keeping little fat cells from getting big... perhaps by blocking certain enzymes that let fat cells swell." A study report suggests that CLA could help people lose weight, primarily by reducing overall fat mass. Noni contains the essential fatty acids including Linoleic acid. Hence taking Noni a long term basis helps to reduce body fat more quickly and effectively

· In the body, the amino acid tryptophan is converted to 5-HTP(5-hydroxy tryptophan), which is converted to serotonin. 5-HTPis a precursor to serotonin, the neurotransmitter that signals our brains to feel happy and content. 5-HTP is normally used then to induce quality sleep and fight depression. It is theorized that many people are overweight because their bodies have a decreased conversion of the essential amino acid tryptophan to 5-HTP and, as a result, have lower levels of serotonin. Noni contains the amino acids tryptophan in rich quantity and that get convert to serotonin in our body and thus helps to increase the body serotonin level . 5-HTP is believed to cause a feeling of early satiation. In other words, you may get full faster, causing you to eat less. Thus, 5-HTP is believed to be especially helpful for people who have a difficult time controlling how much they eat, specifically high-sugar and/or carbohydrate foods.

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